منابع مشابه
MicroRNAs: new players in an old game.
O ne of the cardinal steps in regulating gene expression is mRNA decay, and the numerous pathways and mechanisms that exist to regulate it underscore its importance. mRNA decay is regulated by trans-acting factors that assemble on cis-acting elements (1, 2). Together, they serve to upor downregulate a given mRNA. Some of the mechanisms that regulate mRNA levels involve surveillance pathways suc...
متن کاملAutophagy and microtubules - new story, old players.
Both at a basal level and after induction (especially in response to nutrient starvation), the function of autophagy is to allow cells to degrade and recycle damaged organelles, proteins and other biological constituents. Here, we focus on the role microtubules have in autophagosome formation, autophagosome transport across the cytoplasm and in the formation of autolysosomes. Recent insights in...
متن کاملMetabolism and Cancer: Old and New Players
1 Laboratoire de Biologie Moléculaire et Cellulaire du Cancer (LBMCC), Hôpital Kirchberg, 9 rue Edward Steichen, L-2540 Luxembourg, Luxembourg 2 Laboratory of Biochemistry and Cellular Biology (URBC), NAmur Research Institute for LIfe Science (NARILIS), University of Namur, 5000 Namur, Belgium 3Cancer Chemoprotection Program, Linus Pauling Institute, 307 Linus Pauling Science Center, Oregon Sta...
متن کاملInhibitors of V-ATPases: old and new players.
V-ATPases constitute a ubiquitous family of heteromultimeric, proton translocating proteins. According to their localization in a multitude of eukaryotic endomembranes and plasma membranes, they energize many different transport processes. Currently, a handful of specific inhibitors of the V-ATPase are known, which represent valuable tools for the characterization of transport processes on the ...
متن کاملRenal acid-base transport: old and new players.
Systemic acid-base homeostasis is the product of complex interactions between metabolism, regulated exhalation of CO2 by the lungs and acid or base excretion by the kidneys. The importance of renal acid-base transport has been highlighted by mutations identified in several proteins involved in this task in patients with inborn forms of renal tubular acidosis. The underlying mechanisms of diseas...
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ژورنال
عنوان ژورنال: M/C Journal
سال: 1998
ISSN: 1441-2616
DOI: 10.5204/mcj.1729